Showing posts with label Kidney Failure Stage. Show all posts
Showing posts with label Kidney Failure Stage. Show all posts

Tuesday, August 4, 2015

Stage of Renal Failure

For each of us to better to learn all kinds of life, we should understand a lot of common sense knowledge related diseases. The following will tell you about the various stages of renal failure:

1, decompensated renal function:

Normal glomerular filtration rate of 120 ml per minute. This reduction of glomerular filtration rate to 30-60 ml / min, reduce the renal unit of about 20% -25%. Despite the loss of renal reserve capacity at this time, but for the excretion of metabolites, regulation of water, electrolyte and acid-base balance is still good, so no special clinical manifestations, blood urea nitrogen muscle enzymes are usually normal or slightly elevated sometimes.

2, azotemia:

This reduction of glomerular filtration rate to 25 ml / min, renal units reduced by 50% -70%, renal dysfunction concentrated, there nocturia or polyuria, varying degrees of anemia, often azotemia, creatinine , urea nitrogen levels. Clinically, fatigue, loss of appetite, mild nausea and general discomfort. This neglect of renal function, such as additional load protection or body, such as severe vomiting, diarrhea, caused by hypovolemia, severe infection and use of nephrotoxic drugs, can cause rapid kidney function decline and failure.


3, renal failure (uremia preliminary):

Reduction in glomerular filtration rate to 10-15 ml per minute, renal unit decrease of approximately 70% -90%, severely impaired renal function, metabolism and can not maintain water and electrolyte and acid-base balance of the body. Impossible to maintain a stable internal environment, resulting in serum creatinine, blood urea nitrogen increased significantly, diluted urine concentration dysfunction, acidosis, sodium retention, low calcium, high phosphorus, potassium and other balance disorders performance. Chronic renal failure can be cured? May have significant anemia and gastrointestinal symptoms such as nausea, vomiting, loss of appetite. You may also have neuropsychiatric symptoms, such as fatigue, lack of concentration, lack of energy and so on.

4, uremia:

Glomerular filtration rate decreased to 10 ml -15 ml per minute or less, more than 90% reduction in renal units, this period is late chronic renal failure, renal failure symptoms more pronounced above, showing multiple organ failure, such as the gastrointestinal tract, nervous system, cardiovascular, blood system, respiratory system, skin and metabolic system imbalance. Clinically manifested as nausea, vomiting, irritability, increased blood pressure, palpitation, chest tightness, not supine, breathing difficulties, severe anemia, convulsions, coma and severe, often hyperkalemia, hyponatremia, hypocalcemia, high blood phosphorus disease. This need to rely on dialysis to sustain life. Often due to hyperkalemia, cerebral edema, pulmonary edema, heart failure and sudden death.

Through detailed and specific about the situation concerning the various stages of renal failure, hope to help a patient in need as well as family members of patients.


If you have any questions you want advice, you can contact us by email: chinakidneyhospital@gmail.com or Tel: +8613633219293.

Saturday, October 11, 2014

What Is The Chronic Renal Failure In Installment

Chronic renal failure (CRF) refers to a variety of causes chronic progressive renal damage, resulting in a dramatic drop in the kidneys can not maintain basic functions appear to clinical metabolites retention, water, electrolytes, acid-base balance, involvement of the whole body system the main clinical manifestations of the syndrome. So, chronic renal insufficiency how staging? Now we learn together.



How staging of chronic renal

Chronic renal insufficiency is divided four, you said that four. Generally based on serum creatinine and glomerular filtration rate to points.

First period: chronic renal insufficiency compensatory deadline: when impaired renal units does not exceed 50% of normal(GFR50 ~ 80ml / min) renal function because it can not appear compensatory and blood urea nitrogen (BUN) and other metabolites retention, serum creatinine (Scr) to maintain normal levels (serum creatinine 133 ~ 177ummol / l, 1.5 ~ 2.0mg / dl), usually clinically asymptomatic.

Phase II: chronic renal insufficiency in decompensated: impaired renal units remaining kidney function is less than 50% of normal (GFR20 ~ 50ml / min) serum creatinine of 177 ~ 442umol / l (2 ~ 5mg / dl), urea nitrogen, increased by more than 7.1mmol / l, (20mg / dl), clinical fatigue, mild anemia, loss of appetite and other symptoms.

Phase III: renal failure: serum creatinine of 442 ~ 707ummol / l (5 ~ 8mg / dl), creatinine clearance rate dropped to 10 ~ 20ml / min, blood urea nitrogen rose to 17.9 ~ 28.6mmol (50 ~ 80mg / dl ). Patients with severe anemia, metabolic acidosis, calcium and phosphorus metabolism, water and electrolyte metabolism disorders.


Phase IV: uremia: serum creatinine of 707ummol / l (8mg / dl) or more, creatinine clearance rate of 10ml / min or less, urea nitrogen 28.6mmol / l (80mg / dl) or more, acidosis symptoms, systemic each system symptoms are severe.