What Is The Chronic Renal Failure In Installment

Chronic renal failure (CRF) refers to a variety of causes chronic progressive renal damage, resulting in a dramatic drop in the kidneys can not maintain basic functions appear to clinical metabolites retention, water, electrolytes, acid-base balance, involvement of the whole body system the main clinical manifestations of the syndrome. So, chronic renal insufficiency how staging? Now we learn together.

How staging of chronic renal

Chronic renal insufficiency is divided four, you said that four. Generally based on serum creatinine and glomerular filtration rate to points.

First period: chronic renal insufficiency compensatory deadline: when impaired renal units does not exceed 50% of normal(GFR50 ~ 80ml / min) renal function because it can not appear compensatory and blood urea nitrogen (BUN) and other metabolites retention, serum creatinine (Scr) to maintain normal levels (serum creatinine 133 ~ 177ummol / l, 1.5 ~ 2.0mg / dl), usually clinically asymptomatic.

Phase II: chronic renal insufficiency in decompensated: impaired renal units remaining kidney function is less than 50% of normal (GFR20 ~ 50ml / min) serum creatinine of 177 ~ 442umol / l (2 ~ 5mg / dl), urea nitrogen, increased by more than 7.1mmol / l, (20mg / dl), clinical fatigue, mild anemia, loss of appetite and other symptoms.

Phase III: renal failure: serum creatinine of 442 ~ 707ummol / l (5 ~ 8mg / dl), creatinine clearance rate dropped to 10 ~ 20ml / min, blood urea nitrogen rose to 17.9 ~ 28.6mmol (50 ~ 80mg / dl ). Patients with severe anemia, metabolic acidosis, calcium and phosphorus metabolism, water and electrolyte metabolism disorders.


Phase IV: uremia: serum creatinine of 707ummol / l (8mg / dl) or more, creatinine clearance rate of 10ml / min or less, urea nitrogen 28.6mmol / l (80mg / dl) or more, acidosis symptoms, systemic each system symptoms are severe.