Monday, October 13, 2014

Therapeutic Approach Purpura Nephritis

Purpura nephritis disease is a type belonging to a rare kidney disease. In everyday life, it is easy to produce relapse due to allergies, then the treatment of this disease pathway, what does?

1) Vasodilators: Why vasodilator because glomerular deposition of immune complexes appear once, they will appear on the capillaries of various types of cells in ischemia and hypoxia, the vasodilator purpose is to try to improve renal blood circulation? blood status of each system, relieve ischemia and hypoxia each kidney inherent cells, mesangial cells for the next repair to provide a good environment.

2) Anti-inflammatory: Why? Do is to reduce inflammation in inflammatory cell infiltration, reduce further damage mesangial cells.

3) Anticoagulant: increase in inflammatory cells in the blood, will increase the viscosity of the blood to a certain extent, which increases the glomerular capillary micro thrombosis. The use of anticoagulant drugs is to reduce the pressure of thrombosis, in order to lay the foundation for the repair of mesangial cells.

4) Degradation: glomerular capillaries and blood vessels increase in inflammatory cells in the micro-thrombosis, and immune complex deposition resulting from allergic purpura, will glomerular mesangial cells in cytoplasmic accumulation and deposits increased extracellular matrix. To do this go through the use of related drugs to continue to degrade the extracellular matrix deposition and make excreted with the urine.


These are several ways to treat purpura nephritis way, if you have any questions, you can contact our online experts or contact me via E-mail liu476qiang@gmail.com.

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