Proteinuria Classification

Kidney disease such as proteinuria lives belong among relatively common type of the disease, but also affect the health of patients with kidney to a patient brought ordinary people can not imagine the pain, so we hope for patients with this disease can actively correct treatment, then to We need to think properly treat the type of disease suffering from symptomatic treatment.

1. Functional proteinuria

Mild proteinuria is a benign, after removal of the reason may soon disappear, 24h urinary protein generally not more than 0.5g, which produces the mechanism is unclear, it may be affected by external factors cause kidney renal vascular spasm, congestion, kidney a small increase in glomerular filtration rate, seen in strenuous exercise, long march, high temperature environment. Fever, cold environment, nervousness, congestive heart failure.

2. pathological urinary protein

It is the most common and significant proteinuria seen in primary or secondary kidney disease, generally more protein in urine, urine sediment in clinical manifestations of red blood cells, white blood cells, camp type, edema, hypertension and so on.

3. orthostatic urinary protein

It features the appearance of proteinuria and body position, long-term standing, walking, etc. lordosis. Orthostatic proteinuria is due to renal vein distortion or compression of the left renal vein lordosis of the spine, causing temporary circulatory disorders caused by supine 1h urine protein disappear or decrease. When suspected orthostatic proteinuria, were measured in the morning before getting up, significant differences in the urine protein may occur after getting up. Lordosis caused by, ask the patient standing against the wall for 10 min observation, if the urine protein appears to confirm the diagnosis. Diagnose orthostatic proteinuria should be careful, take time followed generally observed more than five years, the disease did not change, continued normal renal function, for diagnosis. Once the presence of persistent proteinuria, when the function damage, should be promptly corrected diagnosis and timely treatment measures.

Proteinuria such diseases, we must not blindly treatment, must be based on the type of interest contained in the symptomatic treatment of patients willing to find some relief for each proteinuria disease disease, reducing kidney disease to patients bring harm.

If you have any questions you want advice, you can contact us by email: chinakidneyhospital@gmail.com or Tel: +8613633219293.

Diseases easily confused with proteinuria

1. edema with proteinuria

Swollen with severe proteinuria mostly nephrogenic edema. Except with mild proteinuria seen in nephrogenic edema can also be seen cardiogenic edema. Pregnancy edema, proteinuria and edema more common in gestosis.

2. pregnancy proteinuria

In general, the normal protein in the urine rarely, no more than 7 ~ 10mg / 24h, with ordinary urinalysis undetectable. In fetal urine, when urine protein content increased, ordinary urinalysis can be measured, said fetal proteinuria. If the urine protein ≥3.5g / 24h, then known as proteinuria.

3. hematuria with proteinuria

Renal means from the glomerular hematuria, clinical manifestations of isolated hematuria, or hematuria with proteinuria. If the treatment is not complete, recurrent or loss of government mistreatment, illness can not be effectively controlled, resulting in uremia.

4.The low molecular weight proteinuria

Low molecular weight proteinuria is due to renal tubular damage, the warp back to normal glomerular filtration of protein malabsorption due.

Tips, these symptoms are common in the above, we must pay attention to changes, a lot of patients edema and, therefore, we should pay attention to their diet, avoid fatigue, and that patients should healthy life, do not stay up all night to maintain good mentality choose the right treatment, so as to ease their pain.


If you have any questions you want advice, you can contact us by email: chinakidneyhospital@gmail.com or Tel: +8613633219293.

A Large Amount of Proteinuria Will Endanger Life?

Under normal circumstances, urine contains trace protein, known as proteinuria, but if the high protein content in urine, then we should pay attention, because it could mean proteinuria kidney problem. Well, it would threaten life?

Many patients with chronic nephritis was diagnosed with proteinuria, even if not pay attention, because the body does not feel uncomfortable, neither pain nor itch, as if he did not have the same treatment. However, under normal circumstances, normal 24-hour urine protein in the range of ≦ 0.15g, because proteins in the blood filter membrane in the kidney, the protein is unable to pass this layer of the film, the film can only be a small molecule material, so normal urine is generally not a protein. So, too proteinuria what harm? Great loss of chronic nephritis proteinuria occurred not only nutritious protein, and glomerular lesions aggravated damage.

In addition, under normal circumstances, would filter out some of the glomerular small molecule protein, but can be tubular reabsorption back into the blood, but a large number of tubular proteinuria cause long-term overload, this will result in renal tubular damage, studies have confirmed that one of harm proteinuria is an independent risk factor for causing uremia, its greatest harm that drug eclipse kidney disease to accelerate the development of uremia. However, the main factor uremia life-threatening.


In short, proteinuria, if unchecked, lead to uremia can cause life-threatening.

Proteinuria is a sign of kidney disease?

Here to tell us about proteinuria symptoms mentioned proteinuria many people will be confused with foamy urine, in fact, does not mean bubble urine proteinuria, for most people, urine is normal when there is a bubble phenomenon. Generally, under normal circumstances, urine contains a number of organic and inorganic substances, so that urine and some bubbles strong tension, so that bubbles in the urine does not necessarily indicate a health problem.

So, conversely, when proteinuria usually ranked foamy urine. And this characteristic is often foamy urine urine surface layer of tiny bubbles floating, long time does not disappear. If the bubble urine and accompanied by urinary frequency, urgency, dysuria, or edema, hypertension, or polydipsia, polyuria, polyphagia, when thirst and other symptoms, in this case, it is best to go to the hospital to determine whether the true proteinuria, to avoid delays in treatment.

We need a clear understanding that, although proteinuria is one of the typical symptoms of kidney disease, proteinuria symptoms but not necessarily the kidney disease, for example, proteinuria may occur after strenuous exercise, then this part of the sport proteinuria, the examiner may review the results again in a few days after the remainder.


In addition there is a functional proteinuria, often occurs in healthy young or adult, found in strenuous exercise (or tired), nervousness, after exposure to cold, fever and eating more high-protein foods. The main mechanism of this proteinuria is subject to certain factors that stimulate the kidneys, leading to renal vascular spasm or congestion, increase in glomerular permeability. After removing the cause of urinary protein can quickly disappear, the other may also physiologic orthostatic proteinuria. Therefore, the judgment is what caused proteinuria, but also to seek medical help, his laboratory test results back to the doctor for the comprehensive, the doctor will give a clear diagnosis.

What is the Proteinuria

Under normal circumstances, as the glomerular filtration effect on the choice of plasma protein and renal tubular heavy drain function, people only contains trace protein in urine, ingredients include:
(1) plasma proteins, due to stop the glomerular capillary on the plasma macromolecular protein, it mainly for the urine in the medium and small molecules plasma proteins such as albumin, 2 microglobulin immunoglobulin light chain, beta, and some enzymes such as lysozyme, amylase and lactate dehydrogenase, etc.

(2) urinary tract secretion proteins, mainly for renal tubular secretion or damage out of the protein such as Tamm Horsfall protein and urinary tract secretion or injury, inflammation effusion protein, etc.Because the quantity is little, qualitative procuratorial negatie urine protein, urine stereotypes 24 hours urinary protein quantitative is generally not more than 150 mg.When urine protein content is more than the normal range, qualitative procuratorial urine protein positive urine stereotypes or 24 hours urinary protein quantitative 150 mg is the proteinuria.

Proteinuria can be divided into:

(1) functional urinary system without organic disease, urinary protein temporary to appear, to a lesser degree, short duration, triggers can be faded after lifting.More because of the factors of internal and external environment changes such as body strong motion, fever, cold stimulation, mental stress, the sympathetic nervous excitement, and the application of vascular active agent of renal vascular spasm or congestion caused by temporary sexual function change, increase glomerular capillary wall permeability.When the influence factors to eliminate, urine protein natural dies.24 hours urinary protein quantitative generally less than 0.5 g, see more at teenagers.


(2) orthostatic proteinuria is also called sexual proteinuria.In establishing or spine lordosis of proteinuria.Set position, may lordosis spinal compression renal vein or set down for too long the kidney, the renal vein distortion caused by renal vein blood, lymph and blood circulation suffocate.Its characteristics for a morning or decubitus negatie urine protein, activity or long up getting up, urine protein positive, lay down and then negative.Quantitative generally less than lg, 24 hours urinary protein found in young people.