Friday, August 22, 2014

What is the Proteinuria

Under normal circumstances, as the glomerular filtration effect on the choice of plasma protein and renal tubular heavy drain function, people only contains trace protein in urine, ingredients include:
(1) plasma proteins, due to stop the glomerular capillary on the plasma macromolecular protein, it mainly for the urine in the medium and small molecules plasma proteins such as albumin, 2 microglobulin immunoglobulin light chain, beta, and some enzymes such as lysozyme, amylase and lactate dehydrogenase, etc.

(2) urinary tract secretion proteins, mainly for renal tubular secretion or damage out of the protein such as Tamm Horsfall protein and urinary tract secretion or injury, inflammation effusion protein, etc.Because the quantity is little, qualitative procuratorial negatie urine protein, urine stereotypes 24 hours urinary protein quantitative is generally not more than 150 mg.When urine protein content is more than the normal range, qualitative procuratorial urine protein positive urine stereotypes or 24 hours urinary protein quantitative 150 mg is the proteinuria.

Proteinuria can be divided into:

(1) functional urinary system without organic disease, urinary protein temporary to appear, to a lesser degree, short duration, triggers can be faded after lifting.More because of the factors of internal and external environment changes such as body strong motion, fever, cold stimulation, mental stress, the sympathetic nervous excitement, and the application of vascular active agent of renal vascular spasm or congestion caused by temporary sexual function change, increase glomerular capillary wall permeability.When the influence factors to eliminate, urine protein natural dies.24 hours urinary protein quantitative generally less than 0.5 g, see more at teenagers.


(2) orthostatic proteinuria is also called sexual proteinuria.In establishing or spine lordosis of proteinuria.Set position, may lordosis spinal compression renal vein or set down for too long the kidney, the renal vein distortion caused by renal vein blood, lymph and blood circulation suffocate.Its characteristics for a morning or decubitus negatie urine protein, activity or long up getting up, urine protein positive, lay down and then negative.Quantitative generally less than lg, 24 hours urinary protein found in young people.

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