The Clinical Manifestations of Chronic Interstitial Nephritis

Chronic interstitial nephritis is often hidden, chronic or acute onset, chronic inflammation due to renal interstitial change, mainly for the fibrotic tissue hyperplasia, renal tubular atrophy, reason often have their common clinical manifestations.

Chronic interstitial nephritis is often hidden, chronic or acute onset, chronic inflammation due to renal interstitial change, mainly for the fibrotic tissue hyperplasia, renal tubular atrophy, reason often have their common clinical manifestations.

1. Patients are often characterized by increased urine or night urine gradually, accompanied by varying degrees of nonspecific symptoms such as poor appetite, lack of power, angular, generally no edema, can some cases without any clinical symptoms, but only in a medical or because of other illnesses, it found that slight changes in urine, kidney function decline, anemia, renal bone disease rather than the disease.Some patients after asking the history found that the medical history or exposure to the physical and chemical factors.Part caused by systemic disease can have the performance of the primary disease.

2. Routine urine is usually characterized by mild proteinuria (trace ~ + qualitative, quantitative general < 0.5 g/d), urine protein often tubular proteinuria for small molecules.Can have a small amount of white blood cells in urine sediment, usually free of red blood cells and tube type.Laboratory tests that can appear low proportion of urine, glycosuria, amino acid, phosphate, alkaline urine urine and low phosphorus concentration, hypercalcemia, hyponatremia, high potassium or hypokalemia and renal tubular acidosis.

3. If accompanied by nipple necrosis, can appear in the course of high fever, lower back pain, gross hematuria and urinary tract irritation, a common cause for diabetes, pyelonephritis, analgesic nephropathy, urethral obstruction or vasculitis.Acute nipple necrosis can appear acute kidney failure, necrotic tissue fragments can be found in the urine sediment visible imaging circular shadow or filling defect of the renal pelvis, chronic renal medulla visible and renal papilla calcified shadows, clinical urine concentration function.

4. Chronic interstitial nephritis) can be affected and blood vessels, causing the corresponding function is impaired, early as endogenous creatinine clearance rate drop, followed by elevated serum creatinine can be.Late glomerular and vascular involvement, serious can appear the symptom of chronic renal insufficiency, such as nausea, vomiting, anorexia, anemia is often very serious, and the degree of renal impairment.About half of the patients with high blood pressure, but how often less than glomerular nephritis caused by severe hypertension.


Above is acute interstitial nephritis and detailed clinical manifestations of chronic interstitial nephritis, believe that everyone should be on interstitial nephritis should have certain understanding, once found suffering from the disease, want to normal hospital check treatment as soon as possible, lest delay an illness.I wish you health experts.