How to reduce high creatinine level in PKD

"My friend was diagnosed with polycystic kidney disease , her creatinine level has reached 3.8 , while only 20 percent of kidney normal work, so please tell me some treatment to reduce the level of creatinine ." The patient's friends asked us .

Before we answer the questions, we need to know about the root cause of the high creatinine level in PKD. What causes the elevation of the creatinine level?

Polycystic Kidney Disease (PKD) is kind of hereditary kidney disease and the PKD genes make the renal tubular epithelial cells experience phenotype transforming, which leads to the cysts continuously secreting fluids.

With time going by, the number and size of the cysts would expand and they will oppress the normal renal tissues, and finally make the room of the normal tissues. As a result, the kidneys are not able to work well on filtering the extra toxic waste products out of the blood. With time and with decrease of the kidney function, there will protein, blood found in the urine of the patients. And once the creatinine level rises, it shows the kidneys are suffering from serious damage. If treated in time, there is great hope for the patients to keep away from much worse disease conditions.

What’s the right treatment on reducing the creatinine level?

After we have known the root cause of high creatinine level in PKD, we should treat it from the root.

This is to make the damaged tubular epithelial cells fail to secret the fluids by eliminating the active ingredients released by the cells. And then the cysts would stop growth. Besides, we use some Chinese medicines to increase the permeability of the blood circulation of the cysts surface to reabsorbing the cysts fluids which will excrete together with the urine out of the body. On the other side, we also use some Chinese medicines to repair the damaged renal cells and then improve the renal function besides well control of its symptoms and complication. Therefore, the high creatinine in the blood would be removed out of the body and then the high creatinine level would be lowered naturally.


Different patients vary in disease status, and we can help to make an individualized treatment plan after we know more details about the patients’ disease conditions.

What can help the creatinine go down naturally

Diet is one of the influence factors of creatinine value, so the patients with high creatinineshould pay attention to daily diet, in case of creatinine increased by improper diet. So, what is the healthy diet for high creatinine patients? Professional Proposals are as follows:

1. Protein

Protein metabolites is the cause of kidney disease, so that low-protein diet is the most important principle for high creatinine patients. Low-protein diet doesn’t mean that the patients can not take in any protein at all, protein is a kind of nutrient, if the human body lack of protein, workouts are being fueled mostly by the break down of muscle glutamine for that energy, which can produce uremic toxin, so the protein intake should be arranged properly.

Experts suggest that the protein intake for patients with high side of creatinine should be limited to 0.8~1.0 g/day per kilo of weight。Besides, patients should eat high quality protein food such as eggs, milk, thin meat.

2. Calorie

Renal insufficiency patients need enough calories to ensure the efficient absorption of protein, the calories can be replenished by the food with high calorie and low protein such as grease, low protein starch, patients with normal blood glucose can eat sugary food in moderation.

3. Salt

If the patients have high blood pressure or edema, the salt intake should be limited to low salt or no salt.

4. Water

The water intake of high creatinine patients is the total amount of hesternal urine volume superadd 500~700 ml.


In addition to the rules above, patients with high side of creatinine should remain optimistic mood, avoid fatigue and staying up late, take exercise properly, stop smoking and refrain from drinking, form good living habits, in order to recover from kidney disease as soon as possible.

Prevent Kidney Disease Through The Health Diet

Eating healthy can help prevent or control diabetes, high blood pressure and kidney disease. A healthy diet has a balance of fruits, vegetables, whole grains, dairy products, lean meats and beans. Even small changes like limiting salt (sodium) and fat, can make a big difference in your health.

Limit salt

Do not add salt to your food when cooking or eating. Try cooking with fresh herbs, lemon juice or other spices.

Choose fresh or frozen vegetables instead of canned vegetables. If you do use canned vegetables, rinse them before eating or cooking with them to remove extra salt.

Shop for items that say “reduced-sodium” or “low-sodium.”

Avoid processed foods like frozen dinners and lunch meats.

Limit fast food and salty snacks, like chips, pretzels and salted nuts.

Limit fat

Choose lean meats or fish. Remove the skin and trim the fat off your meats before you cook them.

Bake, grill or broil your foods instead of frying them.

Shop for fat-free and low-fat dairy products, salad dressing and mayonnaise.

Try olive oil or canola oil instead of vegetable oil.

Choose egg whites or egg substitute rather than whole eggs.

Medicines may cause Renal Failure

Nowadays there are many drugs which may damage to our kidneys even to cause renal failure. The common medicines which may damage the kidney in the clinical treatment are as follows:

1. Antibiotics and other chemotherapeutic agents. This type of medicine have three classes as following:

Often damage class: amphotericin B, neomycin, cephalosporins Ⅱ.
More often damage class: gentamicin, kanamycin, streptomycin, tobramycin, amikacin, polymyxin, vancomycin, sulfa drugs.

Occasionally damage class: new penicillin (Ⅰ, Ⅱ, Ⅲ), ampicillin, carbenicillin, chlortetracycline, oxytetracycline, cefotaxime (Ⅳ, Ⅴ, Ⅵ), rifampin, ethambutol.

2. Non-steroidal anti-inflammatory analgesic contains indomethacin, ibuprofen, phenylbutazone, piroxicam, aspirin, aspirin compound (APC), phenacetin, antipyrine, aminopyrine, acetaminophen and naproxen acid.

3. Chemotherapy drugs for Cancer includes cisplatin, methotrexate, brilliant toxic mold, mitomycin, nitrosoureas, 5 - fluorouracil.

4. Antiepileptic drugs are including trimethadione and phenytoin sodium.

5. Medicines which have the function of anesthetic, such as ether, methoxyflurane.

6. Metals and complexing agents.

7. Angiography various agents.

8. Others: cyclosporin A, piperazine cimetidine, allopurinol, mannitol, heroin, dextran.

9. Single herb: aristolochia plants, Hook, gossypol, fish guts, gall bladder, cantharidin, centipede, bee venom, motherwort, Aconitum, fruit, tuber, two ugly, Bolbostemma, epazote, croton, aloe , large maple, Neem bark, TCS, Sakura roots, so that a gentleman, Clematis and so on.


There are so many medicines which may damage the kidney, so that it is necessary for us to take medicines under the doctor’s guidance strictly to protect our kidney.

External Factors That Can Cause Kidney Failure

Actually, renal failure is not necessarily caused by the physical condition of people, and some external factors may also lead to the occurrence of kidney failure, so, please have a look at this article puts forward the external situation carefully, and attention

Modern pollution: environment pollution、air pollution、food pollution、nuclear radiation、noise, made much toxic deposit in the body、threaten the health, injure the kidney as well, for a long time have the symptoms of renal failure.

Take medicine blindly: now people took medicine when they had illness, actually many medicines are easy to injure kidney; secondly, the pesticide and fertilizer of in the food are the factors to cause nephritis, nephritis don’t take timely treatment measures, so that cause to the deterioration of condition, at last cause to renal failure.

Irregular life: smoking、drinking、irregular life、too tired, all of these would cause to kidney injury, with the development of condition, in a further way deteriorate into renal failure.

Competitive business、big pressure: many people have great physical and mental pressure、body and mind tired、the decay of vitality, thus have the symptoms of kidney deficiency, such as insomnia、anorexia、weakness、bad temper、neurasthenia, give rise to the occurrence of kidney disease, if take improper treatment and health care, will have renal failure.


The content above is introduced the reason of some external factors may lead to renal failure, so we need to pay more attention to, completes the prevention work, away from renal failure.

The Cause Of Renal Failure

Renal failure has become a more common kidney disease and its etiopathogenesis are many, and even other kidney diseases development to the last also can lead to kidney failure, introduce some possible cause of renal failure

1.Hypovolemia: All kinds of reasons cause bleeding ,kidney and the liquid of gastrointestinal tract lost ,skin liquid lost(such as burn,excessive sweat)cause blood volume insufficiency .Hypovolemia make renal blood perfusion reduce ,GFR decline ,at the same time the sympathetic nerve excitation and vasopressin rise cause the renal blood shrink ,thus making the GFR decline more and causing renal failure .

2.Circulatory insufficiency:All kinds of reasons cause shock ,heart function and others circulatory insufficiency ,thus causing hypoperfusion ,GFR decline .Excessive use hypotensive drugs is also a inducing factors .

3.Serious infection and blood poisoning: All kinds of serious infection ,especially patients with blood poisoning can through renal ischemia and nephrotoxicity mechanism cause renal failure .

4.Serious trauma:Such as burn ,crush injury,serious fracture ,due to shock ,infection and injury make the organization release myohemoglobin ,easily occur renal failure .Serious burn will make a large number of liquid lost and intravascular hemolysis also prone to kidney failure.


5.Liver cirrhosis and ascites: At this time ,plasma renin-angiotensin-aldosterone system has already been activated ,vasopressin secretion increase cause water and sodium retention .Abnormal liver function make the drug detoxification ability decline .At this time if put ascites too fast it is easy to cause kidney failure ,this kind of patients with renal toxicity drugs are also prone to kidney failure .

The Methods Of Preventing Kidney Cyst

Now, kidney cyst disease has been very popular, and it have affected the normal life of people, in order to reduce this effect, we must do some corresponding prevention measures to ensure that our way of life

1、kidney cyst can be divided into many categories,in generally,the cyst of liver and kidney is congenital, it also has single cyst and multiple cyst, sometimes the cyst of liver and kidney can appear at the same time, the cyst of liver and kidney have small effect on the health of people.

2、Patients with kidney cyst should enhance the awareness of protection, they can have normal job and life in the daily life, the patients with big cyst of liver and kidney should pay attention to local trauma.

3、The methods if treating kidney cyst have many, the curative effect are different,we don’t need to treat the cyst which don’t form the oppression of liver and kidney, we don’t also have effective treatment.

4、The pathogenesis of kidney cyst is dangerous, the cyst of liver and kidney have slow development, it don’t appear the canceration, the prognosis is good.
5、The oversize cyst of liver and kidney can form the pressure symptoms or inflammation for viscera or the surrounding organs, they can use needle aspiration treatment or surgical decompression treatment,patients with inflammation should use antimicrobial treatment.

6、The diagnosis of kidney cyst is very important, it is very reliable to diagnose the cyst of liver and kidney through palm print, they don’t need to do more examinations.


Kidney cyst patients should master some of the ways to prevent illness, they can be some exercise, diet and family care, etc