Sunday, February 16, 2014

How to diagnose patients with IgA nephropathy?

Many diseases in the early days of the symptom is not obvious, so it's difficult to diagnosis, and here we discuss some problems about the differential diagnosis of IgA nephropathy?

Hospitals usually adopt the following three methods for diagnosis of IgA nephropathy:

1, streptococcus infection after acute glomerulonephritis and IgA nephropathy phase identification of acute nephritis syndrome, the former is the incubation period is long, self-healing tendency;The latter short incubation period, disease relapse, and combined with laboratory tests (such as C3, ASO) to distinction.

2, thin basement membrane nephropathy is often persistent microscopic haematuria, often have a positive family history of blood in the urine, renal biopsy pathology in IgA negative, diffuse glomerular basement membrane thinning under electron microscope.In general it is not difficult to identify.Iga nephropathy, membrane hyperplasia.

3, secondary glomerular disease of IgA deposits
First,allergic purpura nephritis, renal pathology and immune pathology with IgA nephropathy is the same, but the former is a typical renal outward manifestations, such as skin purpura, joint swelling pain, abdominal pain, and black stool, etc., can be identified.

Second, lupus nephritis immunofluorescence is a bunch more bright (IgG, IgA, IgM, C3, C1q, fibrous protein related antigen positive).In addition, the clinical features of multi-system involvement systemic lupus erythematosus (sle) and immunology examination will help to identify.


How to diagnose patients with IgA nephropathy?The above is the introduction to IgA nephropathy, know the IgA nephropathy matters needing attention, to control patients with better education condition changes, wish you recover at an early date.

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