Saturday, August 22, 2015

Clinical Manifestations of Polycystic Kidney Disease

Polycystic kidney disease occurrence, has its corresponding clinical manifestations, polycystic kidney disease patients but many do not know what the clinical manifestations of this disease have so largely delayed treatment of polycystic kidney disease, let's look Clinical manifestations of polycystic kidney disease. I hope everyone should have their own understanding.

The childhood kidney patients with normal or slightly larger size and shape, age and size of the cyst gradually increasing number and increasing in most cases 40 to 50 years old kidneys volume growth to a considerable extent before the onset of symptoms. Mainly for bilateral renal enlargement, kidney pain, hematuria, and hypertension.

1. kidney enlargement

Progress on both sides of nephropathy asymmetry, size differences, to the late two kidneys may occupy the entire abdominal cavity, renal cyst surface has a lot of cloth to make kidney-shaped irregular, uneven, hard.

2. kidney pain

Often lower back pressure or dull, there are pain, sometimes abdominal pain. Pain may be due to physical activity, walking for too long, sedentary exacerbated after bed reduce. Renal hemorrhage due to move stones or infection is sudden severe pain.

3. hematuria

About half of the patients showed microscopic hematuria, may have episodes of gross hematuria, the Department of the cyst wall caused by ruptured blood vessels. Bleeding for a long time can cause colic clot through the ureter. White blood cells in urine is often accompanied by hematuria and proteinuria, urinary protein less, generally not more than 1.0 g / day. Obviously when pyuria kidney infection, hematuria aggravated, low back pain with fever.


4. Hypertension

Is a common manifestation of polycystic kidney disease, has not increased in serum creatinine before, about half hypertension, which cyst oppression surrounding tissue, activation of the renin - angiotensin - aldosterone system related. The past 10 years, Graham PC, Torre V and Chapman AB confirmed that the disease so normal kidney tissue, increased interstitial between the cyst and cyst epithelial cells adjacent renin granules, and renin secretion. These are closely related to the growth of cysts and hypertension. In other words, the emergence of hypertension cyst is growing rapidly, it can directly affect the prognosis.

Clinical manifestations of polycystic kidney disease is varied, which is the most common cause of high blood pressure is because, in our lives are very common, it is also a reminder of polycystic kidney disease in patients with polycystic kidney disease in the face of their own, they must To learn more about the clinical manifestations of polycystic kidney disease, good treatment. Weekdays have to do prevention.


If you have any questions you want advice, you can contact us by email: chinakidneyhospital@gmail.com or Tel: +8613633219293.

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