Saturday, January 11, 2014
Best Treatment for Shrinking Kidneys
Shrinking kidney is a manifestation of renal dysfunction in patients with the gradual progression of renal disease, and patients’ kidneys are shrinking more and more serious. The key lies in the treatment of renal atrophy grasp the timing of treatment and treatment methods, can seize the favorable opportunity, blocking the formation of fibrotic deterioration link chain, the key to determining the success or failure of the treatment. So also with the treatment of renal atrophy renal failure, uremia linked. Shrinking kidney is a symptom of kidney development to the emergence of late, so the treatment can not simply seek treatment for renal atrophy , you need to come from the whole to seek a solution.
Advances in treatment
After the development of various types of kidney renal failure, uremia, renal atrophy also will be in the field of kidney disease clinical treatment for renal atrophy has held pessimism that renal atrophy treatment without any good way to delay until kidney function only slowly complete loss of kidney transplant to maintain life . But with the development of China's medical cause of kidney disease, kidney disease academia prospects for the treatment of renal atrophy gradually optimistic.
Treatment to roots
To find an effective method for the treatment of renal atrophy, renal atrophy need to explore the underlying causes generated. Kidney invasion by outsiders, inflammation occurs, resulting in cell phenotype transformation occurs gradually with the progress of renal fibrosis, renal parenchymal damage thereby, kidney also will be reduced. The treatment of renal atrophy should also focus on how to stop the treatment of renal fibrosis, the spirit of this view was established with kidney disease will coincide.
Kidney fiber
Treatment of renal atrophy focus: kidney damage tissue repair and restore kidney function and prevent the progression of kidney fibrosis, blocking the kidneys continue to shrink. Specific treatment principle is: to promote apoptosis of muscle fibers into phagocytic cells and immune complexes.
Reduced to increase their synthesis of ECM degradation, damage to the kidneys may also be part of the tissue repair, renal function can be restored gradually, fibroblasts and myofibroblasts apoptosis of immune complexes, it continues to block ECM synthesis and secretion of growth increase degrading enzymes generated within the kidney , enhancing its degradation activity on ECM , reducing ECM destruction of kidney tissue , gradually reversing impaired renal function.
The reason most of renal atrophy resulting kidney diseases without effective treatment may lead to the close relationship of renal atrophy and renal atrophy indicate kidney disease and renal function changes are complementary, when patients with renal atrophy occurs when kidney function has been or is bound incomplete until renal failure - uremia.
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