Check what glomerular nephritis patients

Nephritis is a kind of chronic kidney disease, long development process, have different characteristics in different periods, so the time of diagnosis to determine whether patients with suspected disease, not only, also need to determine which stage of the disease in chronic renal failure, so that targeted for treatment.

General inspection:

1, urinalysis
Urinary anomalies is the basic sign of chronic nephritis.Proteinuria is the main basis of diagnosis of chronic nephritis, urine protein in 1 ~ 3 g/day, urine sediment visible particles tube type and transparent tube type.Most of those with microscopic haematuria, between a few patient can have sex with macroscopic haematuria.
2, renal function examination
Most of the patients with chronic nephritis had a different degree of glomerular filtration rate (GFR), early performance for creatinine clearance decreased, followed by elevated serum creatinine.Can be associated with different degrees of renal tubular function decline, such as distal renal tubular urine concentration is reduced and (or) proximal renal tubular reabsorption function decline.
3, blood tests
Does not change significantly in the early, kidney failure is visible cells are pigment anemia, erythrocyte sedimentation rate significantly faster, reduce plasma albumin, blood cholesterol slightly increased, serum C3 to normal.
4, renal biopsy
Clear kidney pathological types.

Chronic glomerulonephritis should be mainly with the following disease identification:

A, secondary glomerulonephritis, such as lupus nephritis, allergic purpura nephritis, according to the corresponding system performance and specific laboratory examination, generally it is not difficult to identify.
Second, Alport syndrome often starts in adolescents (much) before the age of 10, patients with eye (spherical lens, etc.), ear (sensorineural deafness), kidney (hematuria, mild and moderate proteinuria and progressive renal impairment) anomaly, and have a positive family history (mostly dominant inheritance chain).
Third, other primary glomerular disease
(1) virus infection aslar-pacific perspective glomerulonephritis: clinical light should identify with different virus infection aslar-pacific perspective glomerular nephritis, chronic nephritis the latter mainly for asymptomatic hematuria and (or) proteinuria, edema, high blood pressure and renal function impairment.
(2) after the infection of acute glomerulonephritis: a precursor infection with acute onset of chronic nephritis to identify with the disease.The incubation period is different, the dynamic changes of the serum C3 will help identify;In addition, the outcome of disease, chronic nephritis no self-healing tendencies, a chronic progress, any difference.

Four, primary hypertensive renal damage is significantly higher blood pressure of essential hypertension secondary to chronic nephritis renal damage identification (that is, the benign renal arteriole sex sclerosis), the latter has the long-term high blood pressure, first followed the kidney damage, the clinical function of distal renal tubular injury (such as urine concentration is reduced, nocturia more) than the glomeruli injury early, urine change slightly (trace to mild proteinuria, but those with microscopic haematuria and tube type), often have high blood pressure, the other target organs (heart, brain) complications.