Friday, January 24, 2014

What Tests Can Be Used to Diagnose Lupus Nephritis

In most cases, Lupus Nephritis patients have proteinuria and hematuria or they present Nephrotic Syndrome, along with swelling, high blood pressure and decline of kidney function. All of these symptoms and signs remind patients to do some tests, for diagnosing Lupus Nephritis. Today, we are here to talk about Lupus Nephritis diagnosis.
Acute fever is more common with lupus nephritis;Most patients had anemia appearance;Facial butterfly erythema characteristic for change.May be accompanied by joint swelling, hair loss, skin rashes or pericardial effusion, heart murmur, hepatosplenomegaly, swollen lymph nodes, and different degree of swelling or chest water, etc.
Most renal involvement occurs after kidney outward manifestations such as fever, arthritis, skin rash
es, heavy cases lesions often quickly involving serous, heart, lungs, liver, hematopoietic organs and other body tissues, and with the corresponding clinical manifestations.About a quarter of the patients with kidney damage as starting performance.For reproductive age women with kidney disease should be routine inspection immunoserology indicators associated with the disease.
Kidney disease expert introduction:
With lupus nephritis routine urine examination may have different levels of urine protein, microscopic haematuria, white blood cells, red blood cells and urine tube type.
Immunology examination with lupus nephritis: a variety of autoantibodies positive serum, gamma globulin increased significantly, the positive circulating immune complex, low complement hematic disease, especially in the activity.Positive blood lupus erythematosus (sle) cells, the skin lupus band test positive.
Most have moderate anemia with lupus nephritis, accidentally hemolytic anemia, blood leukocytes, platelets most less than 100 x109 / L, blood sedimentation quickly.
Heavy activity associated with lupus nephritis reversibility of Ccr decline in different level, blood urea nitrogen and creatinine increased, reduced or hepatic transaminase heighten blood albumin;End-stage Ccr decreased obviously with lupus nephritis and a significant rise in serum creatinine, blood urea nitrogen.

Imaging examination with lupus nephritis: ultrasound in bilateral renal enlargement tip acute lesions;Some patients with liver and spleen enlargement or pericarditis.Renal biopsy can understand with lupus nephritis pathologic type, disease activity, and determine treatment.Kidney damage as the starting performance of systemic lupus erythematosus (sle), renal biopsy is helpful to diagnosis.

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