In most cases, Lupus Nephritis patients have proteinuria and hematuria or
they present Nephrotic Syndrome, along with swelling, high blood pressure and
decline of kidney function. All of these symptoms and signs remind patients to
do some tests, for diagnosing Lupus Nephritis. Today, we are here to talk about
Lupus Nephritis diagnosis.
Acute fever is more common with lupus
nephritis;Most patients had anemia appearance;Facial butterfly erythema
characteristic for change.May be accompanied by joint swelling, hair loss, skin
rashes or pericardial effusion, heart murmur, hepatosplenomegaly, swollen lymph
nodes, and different degree of swelling or chest water, etc.
Most renal involvement occurs after kidney outward manifestations such as
fever, arthritis, skin rash
es, heavy cases lesions often quickly involving
serous, heart, lungs, liver, hematopoietic organs and other body tissues, and
with the corresponding clinical manifestations.About a quarter of the patients
with kidney damage as starting performance.For reproductive age women with
kidney disease should be routine inspection immunoserology indicators associated
with the disease.
Kidney disease expert introduction:
With lupus nephritis routine urine examination may have different levels of
urine protein, microscopic haematuria, white blood cells, red blood cells and
urine tube type.
Immunology examination with lupus nephritis: a variety of autoantibodies
positive serum, gamma globulin increased significantly, the positive circulating
immune complex, low complement hematic disease, especially in the
activity.Positive blood lupus erythematosus (sle) cells, the skin lupus band
test positive.
Most have moderate anemia with lupus nephritis, accidentally hemolytic
anemia, blood leukocytes, platelets most less than 100 x109 / L, blood
sedimentation quickly.
Heavy activity associated with lupus nephritis reversibility of Ccr decline
in different level, blood urea nitrogen and creatinine increased, reduced or
hepatic transaminase heighten blood albumin;End-stage Ccr decreased obviously
with lupus nephritis and a significant rise in serum creatinine, blood urea
nitrogen.
Imaging examination with lupus nephritis:
ultrasound in bilateral renal enlargement tip acute lesions;Some patients with
liver and spleen enlargement or pericarditis.Renal biopsy can understand with
lupus nephritis pathologic type, disease activity, and determine
treatment.Kidney damage as the starting performance of systemic lupus
erythematosus (sle), renal biopsy is helpful to diagnosis.
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