The cause of the low creatinine

Some friends can appear sometimes the phenomenon of creatinine is low, there are several reasons lead to low creatinine, creatinine is low also can cause a harm to human body, thus the people were concerned, then, what are the reasons of low creatinine?
According to understand, creatinine is testing the most commonly used indicator of renal function, also will check project healthy check-up.Many inspection personnel, their serum creatinine values detected in the normal range, they think kidney function completely no problem.In fact this is a kind of understanding of serum creatinine.Because serum creatinine values cannot be timely and accurate to reflect the status of the kidney.When most of human kidney pathological damage, glomerular filtration rate decline rate is large (over 50%), serum creatinine increased at this time the situation can be clinically apparent.People, therefore, conventional wisdom suggests that, "normal serum creatinine, explain kidney nothing" this a myth, should be corrected.
For the reason of low creatinine is what?
The expert reminds: creatinine material is mainly in the human body muscle metabolism of creatine, creatinine renal excretion through to the in vitro.In general, because the body's muscle mass is relatively stable, so the generation of creatinine is constant, the level of serum creatinine mainly depends on the kidneys of creatinine.Kidney compensatory function is very powerful, if two kidney is normal, so as long as a renal function, serum creatinine can be maintained at normal levels.That is to say, the degree of kidney damage accounted for more than half of the entire kidney, will cause low serum creatinine increased living.Therefore, serum creatinine and cannot reflect the early, mild kidney function decline.
Low creatinine may be associated with anemia, muscular dystrophy, muscle atrophy, leukemia, associated diseases such as diabetes insipidus.Such as creatinine measurements a little lower than creatinine normal, can review it again.
Such as urea nitrogen and creatinine value increases, and urea nitrogen/creatinine ratio is low, this is the reason for low creatinine is suggests the possibility of renal damage.
Urea nitrogen/creatinine ratio, 20 normal.00-100.00, its meaning is mainly when found that urea nitrogen and creatinine values rise, as the difference is that the renal resistance before or renal (kidney) reasons for judgment.If urea nitrogen/creatinine ratio less than 20, kidney disease risk is higher, if urea nitrogen/creatinine ratio is more than 20, is caused by kidney sex before higher probability.
Creatinine is there are many reasons for the lower, the value of urea nitrogen easily influenced by many other factors, so I can't simple reaction of kidney function, low serum creatinine is clearly how afterwards, we will clearly know, creatinine values without muscle disease, is more simple, can be lift to sync with renal function.So when the kidney itself have lesions, urea nitrogen, creatinine, rise, so the urea nitrogen/creatinine ratio about fall within the scope of a certain numerical (less than 20).If the kidney before sex factors, is often of urea nitrogen increased more, so the numerical urea nitrogen/creatinine bigger (more than 20).

The above is the cause of the low creatinine is a detailed description of how to return a responsibility, expert says, the low creatinine is no matter, must first clear reason for low creatinine and main may be malnourished, if creatinine on the high side, should take timely treatment, so as not to damage the kidney, for the development of uremia.